Combination pill effective, but expensive

When are effective medications just too expensive?

Single-pill combination regimens for treatment of HIV-1 infection.

n engl j med 371;3 nejm.org july 17, 2014 248 This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented....

metaphor in education; hidden but effective

abstract the aim of this paper is to illustrate the role of metaphor in education. the main thesis is that the metaphors shape our attitude towards education implicitly.  with this aim in mind, first, the concept of metaphor is briefly introduced, and then three of the most famous metaphors that have been used in education (factories, gardening and travel), and their differences are discussed. ...

Intra-articular morphine and clonidine produce comparable analgesia but the combination is not more effective.

Both intra-articular morphine and clonidine produce analgesia. This study was designed to compare the analgesic effects of the two drugs, used separately and in combination. We studied 90 patients undergoing arthroscopy of the knee under general anaesthesia. Patients were allocated randomly to receive 20 ml of intra-articular isotonic saline solution containing morphine 2 mg, clonidine 150 micr...

EACS: Effective Avoidance Combination Strategy

When navigating in crowds, humans are able to move efficiently between people. They look ahead to know which path would reduce the complexity of their interactions with others. Current navigation systems for virtual agents consider long-term planning to find a path in the static environment and short term reactions to avoid collisions with close obstacles. Recently some mid-term considerations ...